(r)-(+)-alpha-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-aceticacidsodiumsalt
sodium (R)-α-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]cyclohexa-1,4-diene-1-acetate
CAS: 26774-89-0
Molecular Formula: C13H18NNaO4
(r)-(+)-alpha-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-aceticacidsodiumsalt - Names and Identifiers
| Name | sodium (R)-α-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]cyclohexa-1,4-diene-1-acetate |
| Synonyms | 26774-89-0 Cefradine Impurity 12 NSWNOOKQXWSJGP-YEUQMBKVSA-M D-Dihidro phenylglycine Sodium Dane Salt sodium (R)-α-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]cyclohexa-1,4-diene-1-acetate sodium (2R)-2-cyclohexa-1,4-dien-1-yl-2-[[(E)-4-methoxy-4-oxobut-2-en-2-yl]amino]acetate sodium (2R)-cyclohexa-1,4-dien-1-yl{[(1Z)-3-methoxy-1-methyl-3-oxoprop-1-en-1-yl]amino}ethanoate (r)-(+)-alpha-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-aceticacidsodiumsalt (R)-(+)-Alpha-[(3-Methoxy-1-Methyl-3-Oxo-1-Propenyl)Amino]-1,4-Cyclohexadiene-1-Acetic Acid Sodium Salt |
| CAS | 26774-89-0 |
| EINECS | 248-000-1 |
| InChI | InChI=1/C13H17NO4.Na/c1-9(8-11(15)18-2)14-12(13(16)17)10-6-4-3-5-7-10;/h3-4,7-8,12,14H,5-6H2,1-2H3,(H,16,17);/q;+1/p-1/b9-8-;/t12-;/m1./s1 |
(r)-(+)-alpha-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-aceticacidsodiumsalt - Physico-chemical Properties
| Molecular Formula | C13H18NNaO4 |
| Molar Mass | 275.28 |
| Melting Point | 240°C (dec.)(lit.) |
| Specific Rotation(α) | 83 º (c=1, H2O) |
| Storage Condition | Room Temprature |
| Physical and Chemical Properties | Appearance: white or off-white crystalline powder |
| Use | Intermediate cefradine. |
(r)-(+)-alpha-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-aceticacidsodiumsalt - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
(r)-(+)-alpha-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-aceticacidsodiumsalt - Introduction
sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate is a chemical compound with the formula C17H21NO5Na.
Nature:
sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate is a white crystalline powder that is soluble in water. Its pH range is between 7-9.
Use:
sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate are widely used as pharmaceutical intermediates and synthetic raw materials. It is commonly used in the manufacture of drugs such as phenadine, inosine, and pramipexole. It is also used in research areas.
Method:
The preparation of sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate involves a multi-step organic reaction. First, through a series of organic synthesis steps, the synthesis of phenylglycine. Phenylglycine is then condensed with an appropriate aldehyde and reduced to give dihydrophenylglycine. Finally, the dihydrophenylglycine is reacted with an appropriate acid to form the corresponding dihydrophenylglycine hydrochloride, which is then reacted with sodium hydroxide to give sodium (R)-α-[amino]cyclohexa-1,4-diene-1-acetate.
Safety Information:
sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate is relatively safe under normal conditions of use. However, like all chemical substances, appropriate practices and safe operating procedures must be followed. Inhalation of the powder or direct contact with the skin and eyes should be avoided. Wear appropriate personal protective equipment, including lab gloves and goggles, when using the compound. In the case of accidental contact, rinse immediately with plenty of water and seek medical help.
Nature:
sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate is a white crystalline powder that is soluble in water. Its pH range is between 7-9.
Use:
sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate are widely used as pharmaceutical intermediates and synthetic raw materials. It is commonly used in the manufacture of drugs such as phenadine, inosine, and pramipexole. It is also used in research areas.
Method:
The preparation of sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate involves a multi-step organic reaction. First, through a series of organic synthesis steps, the synthesis of phenylglycine. Phenylglycine is then condensed with an appropriate aldehyde and reduced to give dihydrophenylglycine. Finally, the dihydrophenylglycine is reacted with an appropriate acid to form the corresponding dihydrophenylglycine hydrochloride, which is then reacted with sodium hydroxide to give sodium (R)-α-[amino]cyclohexa-1,4-diene-1-acetate.
Safety Information:
sodium (R)-α-[(amino)] cyclohexa-1,4-diene-1-acetate is relatively safe under normal conditions of use. However, like all chemical substances, appropriate practices and safe operating procedures must be followed. Inhalation of the powder or direct contact with the skin and eyes should be avoided. Wear appropriate personal protective equipment, including lab gloves and goggles, when using the compound. In the case of accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 21:01:54
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Spot supply
Product Name: (R)-(+)-α-[(3-Methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-acetic acid sodium salt Visit Supplier Webpage Request for quotationCAS: 26774-89-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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(r)-(+)-alpha-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]-1,4-cyclohexadiene-1-aceticacidsodiumsalt